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Do not use mirtazapine if you have taken an MAO inhibitor such as furazolidoneFuroxoneisocarboxazidMarplanphenelzineNardilrasagilineAzilectselegilineEldeprylEmsamor tranylcypromineParnatein the last 14 daysSeriouslife threatening side effects can occur if you use mirtazapine before the MAO inhibitor has cleared from your body.
Digestive Systemfrequentvomitinganorexiainfrequenteructationglossitischolecystitisnausea and vomitinggum hemorrhagestomatitiscolitisliver function tests abnormalraretongue discolorationulcerative stomatitissalivary gland enlargementincreased salivationintestinal obstructionpancreatitisaphthous stomatitiscirrhosis of livergastritisgastroenteritisoral moniliasistongue edema.
In an in vivo interaction study in healthyCYP2D6 extensive metabolizer patientsn=24mirtazapine30 mg/dayat steady statedid not cause relevant changes in the pharmacokinetics of steady state paroxetine40 mg/daya CYP2D6 inhibitor.
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